SrasV1, 2020, Analysis, bibRecord, 000109

Thiazole Compounds as Antiviral Agents: An Update.

Identifieur interne : 000109 ( 2020/Analysis ); précédent : 000108; suivant : 000110

Thiazole Compounds as Antiviral Agents: An Update.

Auteurs : Inder P. Singh [Inde] ; Shiv Gupta [Inde] ; Sanjay Kumar [Inde]

Source :

Medicinal chemistry (Shariqah (United Arab Emirates)) [ 1875-6638 ] ; 2020.

RBID : pubmed:31203807

Descripteurs français

KwdFr :
- Antiviraux (), Antiviraux (pharmacologie), Relation dose-effet des médicaments, Relation structure-activité, Structure moléculaire, Tests de sensibilité microbienne, Thiazoles (), Thiazoles (pharmacologie), Virus ().
MESH :
- pharmacologie : Antiviraux, Thiazoles.
- Antiviraux, Relation dose-effet des médicaments, Relation structure-activité, Structure moléculaire, Tests de sensibilité microbienne, Thiazoles, Virus.

English descriptors

KwdEn :
- Antiviral Agents (chemistry), Antiviral Agents (pharmacology), Dose-Response Relationship, Drug, Microbial Sensitivity Tests, Molecular Structure, Structure-Activity Relationship, Thiazoles (chemistry), Thiazoles (pharmacology), Viruses (drug effects).
MESH :
- chemical , chemistry : Antiviral Agents, Thiazoles.
- chemical , pharmacology : Antiviral Agents, Thiazoles.
- drug effects : Viruses.
- Dose-Response Relationship, Drug, Microbial Sensitivity Tests, Molecular Structure, Structure-Activity Relationship.

Abstract

Thiazole is a good nucleus owing to its various pharmaceutical applications. Thiazole containing compounds (thiazoles) have shown various biological activities like antioxidant, analgesic, antibacterial, anticancer, antiallergic, antihypertensive, antiinflammatory, antimalarial, antifungal and antipsychotic. The scaffold is present in more than 18 FDA approved drugs and also in more than 70 experimental drugs. Only a few reviews are available in the literature despite its great medicinal importance. During the course of time, this scaffold has been studied extensively for its antiviral activities and provided compounds with activity in the nM range. However, no focused review is available on the compilation of antiviral activities shown by this scaffold.

DOI: 10.2174/1573406415666190614101253
PubMed: 31203807

Affiliations:

Inde

Links to Exploration step

pubmed:31203807

Le document en format XML

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<author><name sortKey="Gupta, Shiv" sort="Gupta, Shiv" uniqKey="Gupta S" first="Shiv" last="Gupta">Shiv Gupta</name>
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<author><name sortKey="Kumar, Sanjay" sort="Kumar, Sanjay" uniqKey="Kumar S" first="Sanjay" last="Kumar">Sanjay Kumar</name>
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<term>Structure moléculaire</term>
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<term>Structure-Activity Relationship</term>
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<term>Relation structure-activité</term>
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<front><div type="abstract" xml:lang="en">Thiazole is a good nucleus owing to its various pharmaceutical applications. Thiazole containing compounds (thiazoles) have shown various biological activities like antioxidant, analgesic, antibacterial, anticancer, antiallergic, antihypertensive, antiinflammatory, antimalarial, antifungal and antipsychotic. The scaffold is present in more than 18 FDA approved drugs and also in more than 70 experimental drugs. Only a few reviews are available in the literature despite its great medicinal importance. During the course of time, this scaffold has been studied extensively for its antiviral activities and provided compounds with activity in the nM range. However, no focused review is available on the compilation of antiviral activities shown by this scaffold.</div>
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Serveur d'exploration SRAS

Thiazole Compounds as Antiviral Agents: An Update.

Thiazole Compounds as Antiviral Agents: An Update.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

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